BCLA CLEAR - Effect of contact lens materials and designs on the anatomy and physiology of the eye

This paper outlines changes to the ocular surface caused by contact lenses and their degree of clinical significance. Substantial research development improve oxygen permeability rigid soft has meant that in many countries issues hypoxia have largely been negated. The ability change axial growth characteristics globe is being utilised help reduce myopia pandemic several studies meta-analyses shown wearing orthokeratology or multifocal can length (and hence myopia).However, effects on blinking, ptosis, function Meibomian glands, fluorescein lissamine green staining conjunctiva cornea, production lid-parallel conjunctival folds lid wiper epitheliopathy received less attention. Contact lens wear produces a subclinical inflammatory response manifested increases number dendritiform cells conjunctiva, cornea limbus. Papillary conjunctivitis also complication all types lenses. Changes schedule (daily disposable from overnight wear) materials (hydrogel SiHy) papillary conjunctivitis, but effect such dendritic cell migration needs further study. These may be associated with decreased comfort confirmatory are needed. affect sensitivity mechanical stimulation, whether these requires investigation.In conclusion, there materials, design schedules over past 20+ years improved safety seen development. However, still occur warrant effort order optimise experience.